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Kumada, Hiroaki; Yamamoto, Kazuyoshi; Yamamoto, Tetsuya*; Nakai, Kei*; Nakagawa, Yoshinobu*; Kageji, Teruyoshi*; Matsumura, Akira*
Applied Radiation and Isotopes, 61(5), p.1045 - 1050, 2004/11
Times Cited Count：12 Percentile：61.44(Chemistry, Inorganic & Nuclear)To carry out the BNCT clinical trials based on accurate dosimetry of several absorbed doses given to a patient, we have developed JCDS which can determine the absorbed doses by numerical simulation. The aim of this study is to improve the accuracy of the BNCT dosimetry efficiently. We have developed the multi-voxel calculation method reconstructing the original voxel model by combining of several voxel cell sizes such as in 5mm, 10mm and 20mm voxel cell. To verify the accuracy of the multi-voxel method, the calculation results were compared with the phantom experimental data. These results proved that the multi-voxel calculation enables JCDS to more accurately estimate the absorbed doses to a patient by efficient calculations.
Kumada, Hiroaki; Yamamoto, Kazuyoshi; Torii, Yoshiya; Matsumura, Akira*; Yamamoto, Tetsuya*; Nose, Tadao*; Nakagawa, Yoshinobu*; Kageji, Teruyoshi*; Uchiyama, Junzo
JAERI-Tech 2003-002, 49 Pages, 2003/03
JAERI-Tech-2003-002.pdf:5.22MB
no abstracts in English
Yamamoto, Kazuyoshi; Kumada, Hiroaki; Kishi, Toshiaki; Torii, Yoshiya; Endo, Kiyoshi*; Yamamoto, Tetsuya*; Matsumura, Akira*; Uchiyama, Junzo; Nose, Tadao*
JAERI-Tech 2002-092, 23 Pages, 2002/12
JAERI-Tech-2002-092.pdf:5.22MB
Thermal neutron flux is determined using the gold wires in current BNCT irradiation, so evaluation of arbitrary points after the irradiation is limited in the quantity of these detectors. In order to make up for the weakness, dose estimation of a patient is simulated by a computational dose calculation supporting system. In another way without computer simulation, a medical irradiation condition can be replicate experimentally using of realistic phantom which was produced from CT images by rapid prototyping technique. This phantom was irradiated at a same JRR-4 neutron beam as clinical irradiation condition of the patient and the thermal neutron distribution on the brain surface was measured in detail. This experimental evaluation technique using a realistic phantom is applicable to in vitro cell irradiation experiments for radiation biological effects as well as in-phantom experiments for dosimetry under the nearly medical irradiation condition of patient.
Kumada, Hiroaki; Torii, Yoshiya
JAERI-Data/Code 2002-018, 158 Pages, 2002/09
JAERI-Data-Code-2002-018.pdf:30.28MB
A boron neutron capture therapy (BNCT) with epithermal neutron beam is expected to treat effectively for malignant tumor that is located deeply in the brain. It is indispensable to estimate preliminarily the irradiation dose in the brain of a patient in order to perform the epithermal neutron beam BNCT. Thus, the JAERI Computational Dosimetry System (JCDS), which can calculate the dose distributions in the brain, has been developed. JCDS is a software that creates a 3-dimentional head model of a patient by using CT and MRI images and that generates a input data file automaticly for calculation neutron flux and gamma-ray dose distribution in the brain by the Monte Carlo code: MCNP, and that displays the dose distribution on the head model for dosimetry by using the MCNP calculation results. JCDS has any advantages as follows; By treating CT data and MRI data which are medical images, a detail three-dimensional model of patinet's head is able to be made easily. The three-dimensional head image is editable to simulate the state of a head after its surgical processes such as skin flap opening and bone removal for the BNCT with craniotomy that are being performed in Japan. JCDS can provide information for the Patient Setting System to set the patient in an actual irradiation position swiftly and accurately. This report describes basic design and procedure of dosimetry, operation manual, data and library structure for JCDS (ver.1.0)
Kumada, Hiroaki; Matsumura, Akira*; Nakagawa, Yoshinobu*; Yamamoto, Tetsuya*; Yamamoto, Kazuyoshi; Torii, Yoshiya
Research and Development in Neutron Capture Therapy, p.529 - 534, 2002/09
no abstracts in English
